Akademik Çıktılar
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Journal Article Citation - WoS: 23Exact solutions of forced burgers equations with time variable coefficients(Elsevier, 2013) Buyukasik, Sirin A.; Pashaev, Oktay K.In this paper, we consider a forced Burgers equation with time variable coefficients of the form U-t + (mu(t)/mu(t))U + UUx = (1/2 mu(t))U-xx - omega(2)(t)x, and obtain an explicit solution of the general initial value problem in terms of a corresponding second order linear ordinary differential equation. Special exact solutions such as generalized shock and multi-shock waves, triangular wave, N-wave and rational type solutions are found and discussed. Then, we introduce forced Burgers equations with constant damping and an exponentially decaying diffusion coefficient as exactly solvable models. Different type of exact solutions are obtained for the critical, over and under damping cases, and their behavior is illustrated explicitly. In particular, the existence of inelastic type of collisions is observed by constructing multi-shock wave solutions, and for the rational type solutions the motion of the pole singularities is described. (c) 2012 Elsevier B.V. All rights reserved.Journal Article Citation - WoS: 16Citation - Scopus: 18Solitary wave solution of nonlinear multi-dimensional wave equation by bilinear transformation method(Elsevier Science Bv, 2007) Tanoglu, GamzeThe Hirota method is applied to construct exact analytical solitary wave solutions of the system of multi-dimensional nonlinear wave equation for n-component vector with modified background. The nonlinear part is the third-order polynomial, determined by three distinct constant vectors. These solutions have not previously been obtained by any analytic technique. The bilinear representation is derived by extracting one of the vector roots (unstable in general). This allows to reduce the cubic nonlinearity to a quadratic one. The transition between other two stable roots gives us a vector shock solitary wave solution. In our approach, the velocity of solitary wave is fixed by truncating the Hirota perturbation expansion and it is found in terms of all three roots. Simulations of solutions for the one component and one-dimensional case are also illustrated. (C) 2006 Published by Elsevier B.V.Peer Review Citation - WoS: 10Citation - Scopus: 11An update on molecular biology and drug resistance mechanisms of multiple myeloma(Elsevier Science inc, 2015) Mutlu, Pelin; Kiraz, Yagmur; Gunduz, Ufuk; Baran, Yusuf; Baran, YusufMultiple myeloma (MM), a neoplasm of plasma cells, is the second most common hematological malignancy. Incidance rates increase after age 40. MM is most commonly seen in men and African-American population. There are several factors to this, such as obesity, environmental factors, family history, genetic factors and monoclonal gammopathies of undetermined significance (MGUS) that have been implicated as potentially etiologic. Development of MM involves a series of complex molecular events, including chromosomal abnormalities, oncogene activation and growth factor dysregulation. Chemotherapy is the most commonly used treatment strategy in MM. However, MM is a difficult disease to treat because of its marked resistance to chemotherapy. MM has been shown to be commonly multidrug resistance (MDR)-negative at diagnosis and associated with a high incidence of MDR expression at relapse. This review deals with the molecular aspects of MM, drug resistance mechanisms during treatment and also possible new applications for overcoming drug resistance. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
